A Dimerization-Dependent Mechanism Drives the Histone Chaperone FACT Facilitation of Nucleosome Reorganization Journal: Science (First Release) Publication Date: May 15, 2025 DOI: 10.1126/science.juq395 Vivid Workshop Data Ati 81 Torrent Apr 2026
Here are the details for the article associated with that identifier: Le Bonheur 1965
This paper investigates the mechanism of the histone chaperone FACT (Facilitates Chromatin Transcription/Transactions), which is essential for managing nucleosome dynamics during transcription and DNA replication. The researchers used cryo-electron microscopy (cryo-EM) to capture the structure of FACT interacting with a partially disassembled nucleosome.